Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | O55096 |
express system | E.coli |
product tag | N-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Dipeptidyl peptidase III (DPP3) is a ubiquitously expressed zinc-dependent peptide cutting enzyme and selectively hydrolyses amide bonds to cleave N-terminal dipeptide fragments off of physiologically important oligopeptides. DPP3 has been found in a multitude of different types of cells and appears to be involved in various physiological processes (e.g. nociception, blood pressure control, protein turnover). |
molecular weight | The protein has a predicted MW of 84.00 kDa. The protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Rat DPP3 Protein 2032
$315.00 – $1,050.00
Summary
- Expression: E.coli
- Pure: Yes (HPLC)
- Amino Acid Range: Ala2-Ala738
Rat DPP3 Protein 2032
protein |
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Size and concentration 100, 500µg and liquid |
Form Liquid |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped with dry ice. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Dipeptidyl peptidase III (DPP3) is a ubiquitously expressed zinc-dependent peptide cutting enzyme and selectively hydrolyses amide bonds to cleave N-terminal dipeptide fragments off of physiologically important oligopeptides. DPP3 has been found in a multitude of different types of cells and appears to be involved in various physiological processes (e.g. nociception, blood pressure control, protein turnover). |
Protein names Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) |
Gene names Dpp3,Dpp3 |
Protein family Peptidase M49 family |
Mass 10116Da |
Function Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (By similarity). Also cleaves Arg-Arg-beta-naphthylamide. |
Catalytic activity BINDING 450; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_note="catalytic"; /evidence="ECO:0000269|PubMed:10387075"; BINDING 455; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_note="catalytic"; /evidence="ECO:0000269|PubMed:10387075"; BINDING 508; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_note="catalytic"; /evidence="ECO:0000250|UniProtKB:Q9NY33" |
Subellular location Cytoplasm. |
Target Relevance information above includes information from UniProt accession: O55096 |
The UniProt Consortium |
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The purity of Rat DPP3 is greater than 95% as determined by SEC-HPLC. |
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Rat DPP3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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