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PE-Labeled Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein 2480

$1,150.00$4,250.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGADGVGK peptide
SKU: 2480parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

AAV53343(HLA-A*11:01)&P61769(B2M)&VVVGADGVGK

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

molecular weight

tbd

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

PE-Labeled Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein 2480

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

ELISA with PE-Labeled Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetr
Immobilized HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) TCR at 1µg/ml (100µl/Well) on the plate. Dose response curve for PE-Labeled Human HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer, His Tag with the EC50 of 96.7ng/ml determined by ELISA.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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