Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&HMTEVVRRC |
express system | HEK293 |
product tag | C-His-Avi |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. |
molecular weight | tbd |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |

PE-Labeled Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer 2487
$1,150.00 – $4,250.00
Summary
- Mammalian expression: HEK293
- Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and HMTEVVRRC peptide
2487
protein |
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Size and concentration 100, 500µg and liquid |
Form Liquid |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped with dry ice. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. |
Protein names Major histocompatibility complex, class I, A |
Gene names HLA-A,HLA-A |
Protein family MHC class I family |
Mass 41449Da |
Target Relevance information above includes information from UniProt accession: A0A140T913 |
The UniProt Consortium |
No results found |
Publications
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