Weight | 1 lbs |
---|---|
Dimensions | 9 × 5 × 2 in |
accession | P09411 |
express system | Baculovirus-Insect Cells |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE |
background | Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which mediates the tumor growth, migration and invasion through phosphorylation some important substrates. |
molecular weight | The protein has a predicted MW of 46.07 kDa same as Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse PGK1 Protein 2395
$300.00 – $1,000.00
Summary
- Expression: Baculovirus-Insect Cells
- Pure: Yes (SDS-PAGE)
- Amino Acid Range: Met1-Val417
Mouse PGK1 Protein 2395
protein |
---|
Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
---|
Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which mediates the tumor growth, migration and invasion through phosphorylation some important substrates. |
Protein names Phosphoglycerate kinase 1 (EC 2.7.2.3) |
Gene names Pgk1,Pgk1 Pgk-1 |
Protein family Phosphoglycerate kinase family |
Mass 10090Da |
Function Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. |
Catalytic activity BINDING 24..26; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 39; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 63..66; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 123; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 171; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 220; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 313; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 344; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 373..376; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7" |
Pathway PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. |
Subellular location Cytoplasm . |
Tissues Testis, lung, brain, skeletal muscle, liver, intestine, and kidney (at protein level). |
Structure Monomer. |
Target Relevance information above includes information from UniProt accession: P09411 |
The UniProt Consortium |
Publications
pmid | title | authors | citation |
---|---|---|---|
We haven't added any publications to our database yet. |
relevant to this product |
---|
# | ||
---|---|---|
Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. |
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.