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Mouse PGK1 Protein 2395

$300.00$1,000.00

Summary

  • Expression: Baculovirus-Insect Cells
  • Pure: Yes (SDS-PAGE)
  • Amino Acid Range: Met1-Val417
SKU: 2395parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P09411

express system

Baculovirus-Insect Cells

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE

background

Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which mediates the tumor growth, migration and invasion through phosphorylation some important substrates.

molecular weight

The protein has a predicted MW of 46.07 kDa same as Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse PGK1 Protein 2395

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which mediates the tumor growth, migration and invasion through phosphorylation some important substrates.
Protein names
Phosphoglycerate kinase 1 (EC 2.7.2.3)
Gene names
Pgk1,Pgk1 Pgk-1
Protein family
Phosphoglycerate kinase family
Mass
10090Da
Function
Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility.
Catalytic activity
BINDING 24..26; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 39; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 63..66; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 123; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 171; /ligand="substrate"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 220; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 313; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 344; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"; BINDING 373..376; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000250|UniProtKB:Q7SIB7"
Pathway
PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.
Subellular location
Cytoplasm .
Tissues
Testis, lung, brain, skeletal muscle, liver, intestine, and kidney (at protein level).
Structure
Monomer.
Target Relevance information above includes information from UniProt accession: P09411
The UniProt Consortium

SDS-PAGE gel of Mouse PGK1 Protein
Mouse PGK1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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