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Mouse OX40 Ligand/TNFSF4 Protein 3398

$330.00$1,100.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Ser51-Leu198
SKU: 3398parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P43488

express system

HEK293

product tag

N-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.

molecular weight

The protein has a predicted MW of 42.6 kDa. Due to glycosylation, the protein migrates to 52-56 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per ug by the LAL method.

Mouse OX40 Ligand/TNFSF4 Protein 3398

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
Protein names
Tumor necrosis factor ligand superfamily member 4 (OX40 ligand) (OX40L) (CD antigen CD252)
Gene names
Tnfsf4,Tnfsf4 Ox40l Txgp1l
Protein family
Tumor necrosis factor family
Mass
10090Da
Function
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Subellular location
Membrane; Single-pass type II membrane protein.
Structure
Homotrimer.
Target Relevance information above includes information from UniProt accession: P43488
The UniProt Consortium

Data

ELISA with Mouse OX40 Ligand/TNFSF4 Protein
Immobilized Mouse OX-40 Ligand, hFc Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Mouse OX40, His Tag with the EC50 of 1.06µg/ml determined by ELISA.
HPLC of Mouse OX40 Ligand/TNFSF4 Protein
The purity of Mouse OX40 Ligand is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse OX40 Ligand/TNFSF4 Protein
Mouse OX40 Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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Documents

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