Mouse NKG2A&CD94 Protein 4267

$315.00 – $1,050.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Asn98-Ile244(NKG2A) & Ile32-Ile179(CD94)

SKU: 4267parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q9WU31(NKG2A)&O54707(CD94)
express system	HEK293
product tag	C-mFc
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
molecular weight	The protein has a predicted MW of18.3 kDa (CD94) and 43.1 kDa (NKG2A). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse NKG2A&CD94 Protein 4267

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
Protein names Natural killer cell receptor NKG2A
Gene names Klrc1,Klrc1 Nkg2a
Mass 27606Da
Subellular location Membrane ; Single-pass type II membrane protein .
Target Relevance information above includes information from UniProt accession: Q9WU31
The UniProt Consortium

Data

The purity of Mouse NKG2A&CD94 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Mouse NKG2A&CD94 Protein

Mouse NKG2A&CD94 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.