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Mouse GPRC5D Protein-VLP 2707

$1,500.00$5,000.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Met1-Leu344
SKU: 2707parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q9JIL6

express system

HEK293

product tag
purity

> 95% as determined by HPLC

background

Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

molecular weight

The target protein has a predicted MW of 39.90 kDa.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse GPRC5D Protein-VLP 2707

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Protein names
G-protein coupled receptor family C group 5 member D
Gene names
Gprc5d,Gprc5d
Protein family
G-protein coupled receptor 3 family
Mass
10090Da
Subellular location
Cell membrane; Multi-pass membrane protein.
Target Relevance information above includes information from UniProt accession: Q9JIL6
The UniProt Consortium

ELISA with Mouse GPRC5D Protein-VLP
Immobilized Mouse GPRC5D VLP (100µl/Well) at 5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.7ng/ml determined by ELISA.
HPLC of Mouse GPRC5D Protein-VLP
The purity of Mouse GPRC5D VLP is greater than 95% as determined by SEC-HPLC.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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