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Mouse CD59a Protein 3292

$270.00$900.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Leu24-Ser96
SKU: 3292parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

O55186 

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

a CD59a fusion protein bound specifically to mouse B cells, and enhanced B cell proliferation in a MLR, demonstrating that B cells express an as yet unidentified ligand for CD59a that aids in B cell activation.

molecular weight

The protein has a predicted MW of 35.17 kDa. Due to glycosylation, the protein migrates to 43-53 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse CD59a Protein 3292

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
a CD59a fusion protein bound specifically to mouse B cells, and enhanced B cell proliferation in a MLR, demonstrating that B cells express an as yet unidentified ligand for CD59a that aids in B cell activation.
Protein names
CD59A glycoprotein (MAC-inhibitory protein) (MAC-IP) (Membrane attack complex inhibition factor) (MACIF) (Protectin) (CD antigen CD59)
Gene names
Cd59a,Cd59a Cd59
Mass
10090Da
Function
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).
Subellular location
Cell membrane; Lipid-anchor, GPI-anchor.
Tissues
Expressed in all tissues examined (liver, kidney, spleen, thymus, brain and heart). Low levels in thymus. Also expressed in mononuclear cells, erythrocytes and platelets. Barely detected in neutrophils.
Target Relevance information above includes information from UniProt accession: O55186
The UniProt Consortium

HPLC of Mouse CD59a Protein
The purity of Mouse CD59a is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse CD59a Protein
Mouse CD59a on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
1. Question: What is the protein concentration of the Mouse CD59a Protein (3292) product?
Answer: The protein concentration of Mouse CD59a Protein (3292) is 0.1 mg/ml.

2. Question: How should I store the Mouse CD59a Protein (3292) after receiving it?
Answer: The Mouse CD59a Protein (3292) should be stored at -80°C upon arrival to ensure long-term stability and activity.

3. Question: Is the Mouse CD59a Protein (3292) compatible with specific applications?
Answer: Yes, the Mouse CD59a Protein (3292) is suitable for various applications, including western blotting, ELISA, immunoprecipitation, and functional assays.

4. Question: Can this Mouse CD59a Protein (3292) be used for cell culture experiments?
Answer: Yes, the Mouse CD59a Protein (3292) can be used for cell culture experiments after reconstitution in the appropriate buffer.

5. Question: Are there any specific handling instructions for using the Mouse CD59a Protein (3292)?
Answer: It is recommended to avoid repeated freeze-thaw cycles and to aliquot the protein upon receiving to avoid multiple freeze-thaw cycles.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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