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Mouse CD3E&CD3D/CD3 epsilon&CD3 delta Protein 4553

$330.00$1,100.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Asp23-Asp108(CD3E) & Phe22-Ala105(CD3D)
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P22646(CD3E)&P04235(CD3D)

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.

molecular weight

The protein has a predicted MW of 36.1 kDa (CD3E) and 35.2 kDa (CD3D). Due to glycosylation, the protein migrates to 50-65 kDa and 40-50 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Mouse CD3E&CD3D/CD3 epsilon&CD3 delta Protein 4553

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Data

HPLC of Mouse CD3E&CD3D/CD3 epsilon&CD3 delta Protein
The purity of Mouse CD3E&CD3D is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Mouse CD3E&CD3D/CD3 epsilon&CD3 delta Protein
Mouse CD3E&CD3D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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