Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | P27811 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. |
molecular weight | The protein has a predicted MW of 19.70 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse CD161 Protein 2796
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gln67-His227
Mouse CD161 Protein 2796
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. |
Protein names Killer cell lectin-like receptor subfamily B member 1A (NKR-P1A) (CD161 antigen-like family member A) (Lymphocyte antigen 55A) (Ly-55A) (NKR-P1.7) (Natural killer cell surface protein P1-2) (NKR-P1 2) (CD antigen CD161a) |
Gene names Klrb1a,Klrb1a Ly55 Ly55a Nkrp1a |
Mass 10090Da |
Function Plays a stimulatory role on natural killer (NK) cell cytotoxicity. |
Subellular location Membrane; Single-pass type II membrane protein. |
Tissues Expressed in natural killer cells. |
Structure Homodimer; disulfide-linked. Interacts with tyrosine kinase LCK (By similarity). |
Target Relevance information above includes information from UniProt accession: P27811 |
The UniProt Consortium |
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The purity of Mouse CD161 is greater than 95% as determined by SEC-HPLC. |
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Mouse CD161 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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We haven't added any publications to our database yet. |
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