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Human Wnt Surrogate-Fc Fusion Protein 2677

$300.00$1,000.00

Summary

  • Expression: HEK293
  • Active: Yes (catalytic)
  • Amino Acid Range:
SKU: 2677parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

0

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE

background

Wnt-3a is regarded as an activator of the canonical Wnt signaling pathway. This activator is expressed in the dorsal midline region and is responsible for spinal cord development. In addition, Wnt-3a plays a regulatory role in autophagy, apoptosis, and regeneration of neurons, neurogenic inflammation and axon regeneration.Wnt-3a promotes the beta-catenin/Tcf pathway which is tumor inducing and can cause cancer when expressed in particular cell populations. It is also one of the most commonly used cytokines for organoid construction.

molecular weight

The protein has a predicted MW of 58.50 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human Wnt Surrogate-Fc Fusion Protein 2677

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Activity assay with Human Wnt Surrogate-Fc Fusion Protein
Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 5.2 ng/mL.
SDS-PAGE gel of Human Wnt Surrogate-Fc Fusion Protein
Human Wnt Surrogate-Fc Fusion on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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