Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q9NZS2 |
express system | HEK293 |
product tag | N-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release. |
molecular weight | The protein has a predicted MW of 20.94 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Human NKp80/CLEC5C Protein 2078
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Leu60-Tyr231
Human NKp80/CLEC5C Protein 2078
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release. |
Protein names Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80) (C-type lectin domain family 5 member C) |
Gene names KLRF1,KLRF1 CLEC5C ML |
Mass 9606Da |
Function Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. |
Subellular location Membrane ; Single-pass type II membrane protein . |
Tissues Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes. |
Structure Homodimer. |
Target Relevance information above includes information from UniProt accession: Q9NZS2 |
The UniProt Consortium |
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The purity of Human NKp80 is greater than 95% as determined by SEC-HPLC. |
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Human NKp80 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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