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Human NKp80/CLEC5C Protein 2078

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Leu60-Tyr231
SKU: 2078parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q9NZS2

express system

HEK293

product tag

N-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release.

molecular weight

The protein has a predicted MW of 20.94 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human NKp80/CLEC5C Protein 2078

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release.
Protein names
Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80) (C-type lectin domain family 5 member C)
Gene names
KLRF1,KLRF1 CLEC5C ML
Mass
9606Da
Function
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
Subellular location
Membrane ; Single-pass type II membrane protein .
Tissues
Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes.
Structure
Homodimer.
Target Relevance information above includes information from UniProt accession: Q9NZS2
The UniProt Consortium

HPLC of Human NKp80/CLEC5C Protein
The purity of Human NKp80 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human NKp80/CLEC5C Protein
Human NKp80 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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