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Human LILRB4/CD85k/ILT3 Protein 4620



  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gln22-His257
Weight1 lbs
Dimensions9 × 5 × 2 in


express system


product tag



> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC


LILRB4, also known as CD85k and LIR-5, ILT-3,   is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

molecular weight

The protein has a predicted MW of 28.6 kDa. Due to glycosylation, the protein migrates to 38-42 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg


Less than 1EU per μg by the LAL method.

Human LILRB4/CD85k/ILT3 Protein 4620

Size and concentration
100, 500µg and lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
> 95% as determined by Tris-Bis PAGE
No information
target relevance


SPR with Human LILRB4/CD85k/ILT3 Protein
Human APOE4, hFc Tag captured on CM5 Chip via Protein A can bind Human LILRB4, His Tag with an affinity constant of 11.87 nM as determined in SPR assay (Biacore T200).
ELISA with Human LILRB4/CD85k/ILT3 Protein
Immobilized Human LILRB4, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-LILRB4 Antibody, hFc Tag with the EC50 of 9.5ng/ml determined by ELISA (QC Test).
HPLC of Human LILRB4/CD85k/ILT3 Protein
The purity of Human LILRB4 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human LILRB4/CD85k/ILT3 Protein
Human LILRB4 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.


Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.



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