Human Kallikrein 3/PSA Protein 2520

$300.00 – $1,000.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Ala18-Pro261

SKU: 2520parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P07288
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), is the most useful biomarker for prostate cancer (PCa). KLK3 is suggested to play a role in regulating cancer growth through anti-angiogenic activity in vivo and in vitro.
molecular weight	The protein has a predicted MW of 27.93 kDa. Due to glycosylation, the protein migrates to 32-38 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human Kallikrein 3/PSA Protein 2520

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), is the most useful biomarker for prostate cancer (PCa). KLK3 is suggested to play a role in regulating cancer growth through anti-angiogenic activity in vivo and in vitro.
Protein names Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase)
Gene names KLK3,KLK3 APS
Protein family Peptidase S1 family, Kallikrein subfamily
Mass 28741Da
Function Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Catalytic activity CATALYTIC ACTIVITY: Reaction=Preferential cleavage: -Tyr-\|-Xaa-.; EC=3.4.21.77;
Subellular location Secreted.
Structure Forms a heterodimer with SERPINA5.
Target Relevance information above includes information from UniProt accession: P07288
The UniProt Consortium

The purity of Human Kallikrein 3 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Human Kallikrein 3/PSA~-Protein

Human Kallikrein 3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.