SPR with Human Interferon omega-1 Protein 2354

Human Interferon omega-1 Protein 2354

$270.00 – $900.00

Summary

Expression: HEK293
Binding assay: Yes (SPR)
Amino Acid Range: Leu22-Ser195

SKU: 2354parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P05000
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Human Interferon omega-1, a type I IFN, also known as IFN-ω1 or IFNW1, it contains a potential N-glycosylation site like human IFN-β. IFN-ω1 binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. All IFN-ω genes analysed to date are devoid of introns. IFN-ω1 has been shown to be well-tolerated in man and to induce reductions of hepatitis C virus RNA levels in a series of human clinical trials.
molecular weight	The protein has a predicted MW of 21.25 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human Interferon omega-1 Protein 2354

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Human Interferon omega-1, a type I IFN, also known as IFN-Ï1 or IFNW1, it contains a potential N-glycosylation site like human IFN-β. IFN-Ï1 binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. All IFN-Ï genes analysed to date are devoid of introns. IFN-Ï1 has been shown to be well-tolerated in man and to induce reductions of hepatitis C virus RNA levels in a series of human clinical trials.
Protein names Interferon omega-1 (Interferon alpha-II-1)
Gene names IFNW1,IFNW1
Protein family Alpha/beta interferon family
Mass 9606Da
Subellular location Secreted.
Target Relevance information above includes information from UniProt accession: P05000
The UniProt Consortium

Data

SPR with Human Interferon omega-1 Protein

Human IFNAR1, His Tag immobilized on CM5 Chip can bind Human Interferon omega-1, His Tag with an affinity constant of 20.96 µM as determined in SPR assay (Biacore T200).

HPLC of Human Interferon omega-1 Protein

The purity of Human Interferon omega-1 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Human Interferon omega-1 Protein

Human Interferon omega-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.