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Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein 4576

$375.00$1,250.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Phe42-Tyr995(ITGA5) acidic tail & Gln21-Asp728(ITGB1) basic tail
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P08648(ITGA5)&P05556(ITGB1)

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Integrin alpha 5/ beta 1, also known as VLA-5, is a widely expressed non-covalent heterodimer of a 160 kDa alpha 5 and a 130 kDa beta 1 Integrin subunit.Alpha 5/ beta 1 is up‑regulated on tumor vasculature and promotes angiogenesis.

molecular weight

The protein has a predicted MW of 111.8 kDa (ITGA5)&83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 100-140 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein 4576

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Data

ELISA with Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Prot
Immobilized Human ITGA5&ITGB1, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-ITGA5&ITGB1 Antibody, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA.
HPLC of Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein
The purity of Human ITGA5&ITGB1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer
Human ITGA5&ITGB1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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