no metadata
Skip to content

Human IL-18 R1/CD218a Protein 4390



  • Expression: HEK293
  • Binding assay: Yes (SPR)
  • Amino Acid Range: Ala19-Arg329
Weight1 lbs
Dimensions9 × 5 × 2 in


express system


product tag



> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC


Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.

molecular weight

The protein has a predicted MW of 38.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg


Less than 1EU per μg by the LAL method.

Human IL-18 R1/CD218a Protein 4390

Size and concentration
100, 500µg and lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
> 95% as determined by Tris-Bis PAGE
No information
target relevance


SPR with Human IL-18 R1/CD218a Protein
Human IL-18 R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 2.38 nM as determined in SPR assay (Biacore T200).
HPLC of Human IL-18 R1/CD218a Protein
The purity of Human IL-18 R1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human IL-18 R1/CD218a Protein
Human IL-18 R1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.


Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.



relevant to this product


No results found


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.