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Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein 2304

$375.00$1,250.00

Summary

  • Expression: E.coli
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGAVGVGK peptide
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

AAV53343(HLA-A*11:01)&P61769(B2M)&VVVGAVGVGK

express system

E.coli

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

molecular weight

The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein 2304

Data

HPLC of Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein
The purity of Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Pr
Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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