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Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer Protein 2187

$750.00$3,000.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ALYVDSLFFL peptide
SKU: 2187parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P79603(HLA-A*02:01)&P61769(B2M)&ALYVDSLFFL

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.

molecular weight

The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer Protein 2187

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
Protein names
MHC class I HLA-A protein (MHC class I antigen)
Gene names
HLA-A*02,HLA-A*02 HLA-A
Protein family
MHC class I family
Mass
9606Da
Target Relevance information above includes information from UniProt accession: P79603
The UniProt Consortium

ELISA with Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer Protein
Immobilized Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA.
HPLC of Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer Protein
The purity of Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer Prote
Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Tetramer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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