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Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein 3329

$750.00$3,000.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and HMTEVVRRC peptide
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A140T913(HLA-A*02:01)&P61769(B2M)&HMTEVVRRC

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.

molecular weight

The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein 3329

Data

HPLC of Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein
The purity of Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Prote
Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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