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Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein 2249

$310.00$1,125.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide
SKU: 2249parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A140T913(HLA-A*02:01)&P61769(B2M)&GLYDGMEHL

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.

molecular weight

The protein has a predicted MW of 50.44 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein 2249

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.
Protein names
Major histocompatibility complex, class I, A
Gene names
HLA-A,HLA-A
Protein family
MHC class I family
Mass
41449Da
Target Relevance information above includes information from UniProt accession: A0A140T913
The UniProt Consortium

HPLC of Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein
The purity of Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Prot
Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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