| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&FLLTRILTI peptide |
| express system | HEK293 |
| product tag | C-His-Avi |
| purity | > 95% as determined by Tris-Bis PAGE;> 93% as determined by HPLC |
| background | Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7). |
| molecular weight | The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
| available size | 100 µg, 500 µg |
| endotoxin | Less than 1EU per μg by the LAL method. |
Human HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer Protein 3244
$750.00 – $3,000.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and FLLTRILTI peptide
Human HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer Protein 3244
| protein |
|---|
| Size and concentration 100, 500µg and lyophilized |
| Form Lyophilized |
| Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Storage buffer Shipped at ambient temperature. |
| Purity > 95% as determined by Tris-Bis PAGE |
| target relevance |
|---|
| Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7). |
| Protein names Major histocompatibility complex, class I, A |
| Gene names HLA-A,HLA-A |
| Protein family MHC class I family |
| Mass 41449Da |
| Target Relevance information above includes information from UniProt accession: A0A140T913 |
| The UniProt Consortium |
 |
| The purity of Human HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer is greater than 93% as determined by SEC-HPLC. |
 |
| Human HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
1. What is the composition of the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244)?
- The product is composed of HLA-A*0201 heavy chain, Beta-2 microglobulin (B2m), and a specific peptide sequence (FLLTRILT I) derived from HBV, designed for binding to T cell receptors.
2. How should I store the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244)?
- The product should be stored at -80°C upon arrival. It is recommended to aliquot the protein into smaller portions to prevent freeze-thaw cycles, which may affect its stability.
3. What applications are suitable for the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244)?
- This Tetramer Protein is ideal for studying HBV-specific T cell responses, T cell receptor interactions, and T cell epitope mapping. It can be used in flow cytometry, immunofluorescence, and other cellular assays.
4. Is the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244) compatible with various cell types?
- Yes, this Tetramer Protein is compatible with a variety of cell types, including T cells, B cells, and other immune cell subsets. It can be used in studies involving both human and mouse models.
5. Can I use the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244) in vivo experiments?
- While this Tetramer Protein is primarily designed for in vitro use, it can potentially be adapted for in vivo studies with appropriate validation. Researchers should consider factors like dosing, delivery methods, and potential immune responses when planning in vivo experiments.
- The product is composed of HLA-A*0201 heavy chain, Beta-2 microglobulin (B2m), and a specific peptide sequence (FLLTRILT I) derived from HBV, designed for binding to T cell receptors.
2. How should I store the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244)?
- The product should be stored at -80°C upon arrival. It is recommended to aliquot the protein into smaller portions to prevent freeze-thaw cycles, which may affect its stability.
3. What applications are suitable for the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244)?
- This Tetramer Protein is ideal for studying HBV-specific T cell responses, T cell receptor interactions, and T cell epitope mapping. It can be used in flow cytometry, immunofluorescence, and other cellular assays.
4. Is the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244) compatible with various cell types?
- Yes, this Tetramer Protein is compatible with a variety of cell types, including T cells, B cells, and other immune cell subsets. It can be used in studies involving both human and mouse models.
5. Can I use the Human HLA-A*0201/B2m/HBV FLLTRILT I Tetramer Protein (3244) in vivo experiments?
- While this Tetramer Protein is primarily designed for in vitro use, it can potentially be adapted for in vivo studies with appropriate validation. Researchers should consider factors like dosing, delivery methods, and potential immune responses when planning in vivo experiments.
Publications
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