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Human GBA/glucocerebrosidase Protein 2951

$750.00$2,500.00

Summary

  • Expression: HEK293
  • Active: Yes (catalytic)
  • Amino Acid Range: Ala40-Gln536
SKU: 2951parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

NP_000148.2

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Glucocerebrosidase (GBA) mutations are the most important genetic risk factor for the development of Parkinson disease (PD). GBA encodes the lysosomal enzyme glucocerebrosidase (GCase).

molecular weight

The protein has a predicted MW of 56.69 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human GBA/glucocerebrosidase Protein 2951

Data

Activity assay with Human GBA/glucocerebrosidase Protein
Measured by its ability to hydrolyze 4-methylumbelliferyl-beta-D-glucopyranoside. The specific activity is >200 pmol/min/µg.
HPLC of Human GBA/glucocerebrosidase Protein
The purity of Human GBA is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human GBA/glucocerebrosidase Protein
Human GBA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

relevant to this product

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