Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | P41439 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures. |
molecular weight | The protein has a predicted MW of 26.63 kDa. Due to glycosylation, the protein migrates to 32-45 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Human FOLR3 Protein 2513
$270.00 – $900.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gln23-Ser245
Human FOLR3 Protein 2513
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures. |
Protein names Folate receptor gamma (FR-gamma) (Folate receptor 3) |
Gene names FOLR3,FOLR3 |
Protein family Folate receptor family |
Mass 9606Da |
Function Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate. |
Subellular location Secreted. |
Tissues Spleen, thymus, bone marrow, ovarian carcinoma, and uterine carcinoma. |
Target Relevance information above includes information from UniProt accession: P41439 |
The UniProt Consortium |
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The purity of Human FOLR3 is greater than 95% as determined by SEC-HPLC. |
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Human FOLR3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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