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Human FLT3 Ligand Protein 2691

$270.00$900.00

Summary

  • Expression: E.coli
  • Active: Yes (cell based assay)
  • Amino Acid Range: Thr27-Ala181
SKU: 2691parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P49771

express system

E.coli

product tag

No Tag

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

molecular weight

The protein has a predicted MW of 17.61 kDa same as Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 0.1 EU per μg by the LAL method.

Human FLT3 Ligand Protein 2691

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Flt-3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Protein names
Fms-related tyrosine kinase 3 ligand (Flt3 ligand) (Flt3L) (SL cytokine)
Gene names
FLT3LG,FLT3LG
Mass
9606Da
Function
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Subellular location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Structure
Homodimer (isoform 2).
Target Relevance information above includes information from UniProt accession: P49771
The UniProt Consortium

ELISA with Human FLT3 Ligand Protein
Immobilized Human FLT3 Ligand, No Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Human FLT3, hFc Tag with the EC50 of 21.7ng/ml determined by ELISA.
Cell based assay with Human FLT3 Ligand Protein
The-ED50-was determined by the dose-dependent stimulation of the proliferation of human AML5 cells is < 1.0 ng/ml. (QC Test)
HPLC of Human FLT3 Ligand Protein
The purity of Human FLT3 Ligand is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human FLT3 Ligand Protein
Human FLT3 Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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