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Human Fas Ligand/TNFSF6 Protein 4897

$420.00$1,400.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Pro134-Leu281
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

AAH17502

express system

HEK293

product tag

N-His

purity

> 95% as determined by Tris-Bis PAGE

background

Fas ligand (FasL, CD95L) is a 40-kDa type II transmembrane protein that binds to Fas (CD95) receptors and promotes programmed cell death. Fas receptors are expressed at higher levels in many tumors than in normal cells.Somewhat paradoxically, elimination of Fas or FasL from tumors also leads to death induced by CD95 receptor/ligand elimination (DICE).

molecular weight

The protein has a predicted MW of 18 kDa. Due to glycosylation, the protein migrates to 20-35 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human Fas Ligand/TNFSF6 Protein 4897

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Data

SPR with Human Fas Ligand/TNFSF6 Protein
Human Fas, His Tag immobilized on CM5 Chip can bind Human Fas Ligand, His Tag with an affinity constant of 19.45 nM as determined in SPR assay (Biacore T200).
ELISA with Human Fas Ligand/TNFSF6 Protein
Immobilized Human Fas Ligand, His Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Human Fas, hFc Tag with the EC50 of 0.19µg/ml determined by ELISA (QC Test).
SDS-PAGE gel of Human Fas Ligand/TNFSF6 Protein
Human Fas Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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Documents

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