Human EGFL7 Protein 3386

$300.00 – $1,000.00

Summary

Expression: E.coli
Functional: Yes (ELISA)
Amino Acid Range: Tyr24-Ser273

SKU: 3386parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q9UHF1
express system	E.coli
product tag	N-His
purity	> 95% as determined by Tris-Bis PAGE
background	Epidermal growth factor-like domain-containing protein 7 (EGFL7), a member of the epidermal growth factor (EGF)-like protein family, is a potent angiogenic factor expressed in many different cell types. EGFL7 plays a vital role in controlling vascular angiogenesis during embryogenesis, organogenesis, and maintaining skeletal homeostasis.
molecular weight	The protein has a predicted MW of 28.4 kDa same as Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per ug by the LAL method.

Human EGFL7 Protein 3386

protein

Size and concentration 100, 500µg and liquid
Form Liquid
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped with dry ice.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Epidermal growth factor-like domain-containing protein 7 (EGFL7), a member of the epidermal growth factor (EGF)-like protein family, is a potent angiogenic factor expressed in many different cell types. EGFL7 plays a vital role in controlling vascular angiogenesis during embryogenesis, organogenesis, and maintaining skeletal homeostasis.
Protein names Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene names EGFL7,EGFL7 MEGF7 UNQ187/PRO1449
Mass 29618Da
Function Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Subellular location Secreted, extracellular space .
Structure Interacts with ITGAV/ITGB3 in an RGD-dependent manner, increasing endothelial cell's motility.
Target Relevance information above includes information from UniProt accession: Q9UHF1
The UniProt Consortium

Data

Immobilized Human EGFL7, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-EGFL7 Antibody, hFc Tag with the EC50 of 17.5ng/ml determined by ELISA.

Human EGFL7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.