Human CLEC10A Protein 3612

$270.00 – $900.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Gln61-Ser316

SKU: 3612parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	Q8IUN9
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	CLEC10A, (C-type lectin domain family 10, member A), as the member of C-type lectin receptors (CLRs), plays a vital role in modulating innate immunity and adaptive immunity and has shown great potential as an immunotherapy target for cancers. However, there is no functional research of CLEC10A in prognostic risk, immunotherapy or any other treatment of lung adenocarcinoma (LUAD).
molecular weight	The protein has a predicted MW of 29.7 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human CLEC10A Protein 3612

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
CLEC10A, (C-type lectin domain family 10, member A), as the member of C-type lectin receptors (CLRs), plays a vital role in modulating innate immunity and adaptive immunity and has shown great potential as an immunotherapy target for cancers. However, there is no functional research of CLEC10A in prognostic risk, immunotherapy or any other treatment of lung adenocarcinoma (LUAD).
Protein names C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD antigen CD301)
Gene names CLEC10A,CLEC10A CLECSF13 CLECSF14 HML
Mass 9606Da
Function Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Subellular location Membrane ; Single-pass type II membrane protein .
Target Relevance information above includes information from UniProt accession: Q8IUN9
The UniProt Consortium

The purity of Human CLEC10A is greater than 95% as determined by SEC-HPLC.

Human CLEC10A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

1. Question: What is the molecular weight of the Human CLEC10A protein (3612)?
Answer: The molecular weight of the Human CLEC10A protein (3612) is approximately 25.3 kDa.

2. Question: How should I store the Human CLEC10A protein (3612) for optimal preservation?
Answer: It is recommended to store the Human CLEC10A protein (3612) at -20°C upon arrival. For long-term storage, aliquot and store at -80°C to avoid freeze-thaw cycles.

3. Question: Is the Human CLEC10A protein (3612) suitable for use in functional assays or protein-protein interaction studies?
Answer: Yes, the Human CLEC10A protein (3612) is suitable for use in functional assays, protein-protein interaction studies, and other biological research applications.

4. Question: Can I use the Human CLEC10A protein (3612) in cell culture experiments?
Answer: Yes, the Human CLEC10A protein (3612) can be used in cell culture experiments as a recombinant protein for various applications, such as stimulating immune responses or studying receptor-ligand interactions.

5. Question: What are some common research applications of Human CLEC10A protein (3612)?
Answer: Common research applications for the Human CLEC10A protein (3612) include immunology studies, glycoprotein research, dendritic cell biology, and innate immunity research.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.