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Human CDH16/Cadherin 16 Protein 2219

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Lys19-Ala786
SKU: 2219parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

O75309

express system

HEK293

product tag

N-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Cadherin (CDH)16/kidney-specific-cadherin was first described as a kidney-specific adhesion molecule and thereafter found expressed also in the thyroid gland. CDH16 is a thyroid-selective and hormone-dependent adhesion protein that might play a role during thyroid development and that may be a useful marker to monitor thyroid carcinomas.

molecular weight

The protein has a predicted MW of MW 84.37 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human CDH16/Cadherin 16 Protein 2219

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Cadherin (CDH)16/kidney-specific-cadherin was first described as a kidney-specific adhesion molecule and thereafter found expressed also in the thyroid gland. CDH16 is a thyroid-selective and hormone-dependent adhesion protein that might play a role during thyroid development and that may be a useful marker to monitor thyroid carcinomas.
Protein names
Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin)
Gene names
CDH16,CDH16 UNQ695/PRO1340
Mass
9606Da
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subellular location
Cell membrane ; Single-pass type I membrane protein .
Tissues
Kidney specific.
Domain
Th
Target Relevance information above includes information from UniProt accession: O75309
The UniProt Consortium

ELISA with Human CDH16/Cadherin 16 Protein
Immobilized Human CDH16, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-CDH16 Antibody, Mouse IgG Tag with the EC50 of 7.5ng/ml determined by ELISA.
HPLC of Human CDH16/Cadherin 16 Protein
The purity of Human CDH16 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human CDH16/Cadherin 16 Protein
Human CDH16 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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