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Human CDH10/Cadherin-10 Protein 2124

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Pure: Yes (SDS-PAGE)
  • Amino Acid Range: Gly55-Ala613
SKU: 2124parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q9Y6N8

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE

background

Cadherins are a large family of cell –cell adhesion molecules involved in inter-cellular adhesion in a wide variety of cell types. In the nervous system, cadherins are known to be crucial to all stages of development, including the early separation of the neural tube from the ectoderm, the segregation of neurones and axons, and the formation of synapses. Cadherin-10 was first partially cloned from human brain, but its mRNA has also been shown to be present in mouse thymus (designated T2-cadherin), mouse testis, and in the developing brain and eye of mouse, rat, and chick.

molecular weight

The protein has a predicted MW of 63.81 kDa. Due to glycosylation, the protein migrates to 72-82 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human CDH10/Cadherin-10 Protein 2124

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Cadherins are a large family of cell –cell adhesion molecules involved in inter-cellular adhesion in a wide variety of cell types. In the nervous system, cadherins are known to be crucial to all stages of development, including the early separation of the neural tube from the ectoderm, the segregation of neurones and axons, and the formation of synapses. Cadherin-10 was first partially cloned from human brain, but its mRNA has also been shown to be present in mouse thymus (designated T2-cadherin), mouse testis, and in the developing brain and eye of mouse, rat, and chick.
Protein names
Cadherin-10 (T2-cadherin)
Gene names
CDH10,CDH10
Mass
9606Da
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subellular location
Cell membrane ; Single-pass type I membrane protein .
Tissues
Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung.
Domain
Th
Target Relevance information above includes information from UniProt accession: Q9Y6N8
The UniProt Consortium

SDS-PAGE gel of Human CDH10/Cadherin-10 Protein
Human CDH10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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