Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q9Y6N8 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE |
background | Cadherins are a large family of cell –cell adhesion molecules involved in inter-cellular adhesion in a wide variety of cell types. In the nervous system, cadherins are known to be crucial to all stages of development, including the early separation of the neural tube from the ectoderm, the segregation of neurones and axons, and the formation of synapses. Cadherin-10 was first partially cloned from human brain, but its mRNA has also been shown to be present in mouse thymus (designated T2-cadherin), mouse testis, and in the developing brain and eye of mouse, rat, and chick. |
molecular weight | The protein has a predicted MW of 63.81 kDa. Due to glycosylation, the protein migrates to 72-82 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Human CDH10/Cadherin-10 Protein 2124
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Pure: Yes (SDS-PAGE)
- Amino Acid Range: Gly55-Ala613
Human CDH10/Cadherin-10 Protein 2124
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Cadherins are a large family of cell –cell adhesion molecules involved in inter-cellular adhesion in a wide variety of cell types. In the nervous system, cadherins are known to be crucial to all stages of development, including the early separation of the neural tube from the ectoderm, the segregation of neurones and axons, and the formation of synapses. Cadherin-10 was first partially cloned from human brain, but its mRNA has also been shown to be present in mouse thymus (designated T2-cadherin), mouse testis, and in the developing brain and eye of mouse, rat, and chick. |
Protein names Cadherin-10 (T2-cadherin) |
Gene names CDH10,CDH10 |
Mass 9606Da |
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
Subellular location Cell membrane ; Single-pass type I membrane protein . |
Tissues Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung. |
Domain Th |
Target Relevance information above includes information from UniProt accession: Q9Y6N8 |
The UniProt Consortium |
Publications
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