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Human CD69/CLEC2C Protein 2833

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Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Ser62-Lys199
SKU: 2833parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q07108

express system

HEK293

product tag

N-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits.

molecular weight

The protein has a predicted MW of 17.07kDa. Due to glycosylation, the protein migrates to 24-27kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human CD69/CLEC2C Protein 2833

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits.
Protein names
Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69)
Gene names
CD69,CD69 CLEC2C
Mass
9606Da
Function
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
Subellular location
Membrane; Single-pass type II membrane protein.
Tissues
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.
Structure
Homodimer; disulfide-linked.
Post-translational modification
Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.
Target Relevance information above includes information from UniProt accession: Q07108
The UniProt Consortium

HPLC of Human CD69/CLEC2C Protein
The purity of Human CD69 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human CD69/CLEC2C Protein
Human CD69 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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