Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q07108 |
express system | HEK293 |
product tag | N-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits. |
molecular weight | The protein has a predicted MW of 17.07kDa. Due to glycosylation, the protein migrates to 24-27kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Human CD69/CLEC2C Protein 2833
$210.00 – $700.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Ser62-Lys199
Human CD69/CLEC2C Protein 2833
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits. |
Protein names Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69) |
Gene names CD69,CD69 CLEC2C |
Mass 9606Da |
Function Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. |
Subellular location Membrane; Single-pass type II membrane protein. |
Tissues Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. |
Structure Homodimer; disulfide-linked. |
Post-translational modification Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes. |
Target Relevance information above includes information from UniProt accession: Q07108 |
The UniProt Consortium |
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The purity of Human CD69 is greater than 95% as determined by SEC-HPLC. |
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Human CD69 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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