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Human CD40 Ligand/TNFSF5 Protein 2335

$300.00$1,000.00

Summary

  • Expression: E.coli
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gln114-Leu261
SKU: 2335parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P29965

express system

E.coli

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE

background

CD40 ligand or CD40L, also called CD154,   is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.

molecular weight

The protein has a predicted MW of 17.15 kDa same as Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human CD40 Ligand/TNFSF5 Protein 2335

Data

ELISA with Human CD40 Ligand/TNFSF5 Protein
Immobilized Human CD40 Ligand, His Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Human CD40, hFc Tag with the EC50 of 0.7µg/ml determined by ELISA.
SDS-PAGE gel of Human CD40 Ligand/TNFSF5 Protein
Human CD40 Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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