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Human CD30 Ligand/TNFSF8 Protein 4501

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gln63-Asp234
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P32971

express system

HEK293

product tag

N-mFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC;

background

CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. The protein is also constitutively expressed on granulocytes and medullary thymic epithelial cells.CD30L is a cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.

molecular weight

The protein has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 62-68 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human CD30 Ligand/TNFSF8 Protein 4501

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. The protein is also constitutively expressed on granulocytes and medullary thymic epithelial cells.CD30L is a cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Protein names
Tumor necrosis factor ligand superfamily member 8 (CD30 ligand) (CD30-L) (CD antigen CD153)
Gene names
TNFSF8,TNFSF8 CD30L CD30LG
Protein family
Tumor necrosis factor family
Mass
9606Da
Function
FUNCTION: Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Subellular location
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein.
Structure
SUBUNIT: Homotrimer. {ECO:0000305}.
Target Relevance information above includes information from UniProt accession : P32971
The UniProt Consortium

Data

ELISA with Human CD30 Ligand/TNFSF8 Protein
Immobilized Human CD30, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Human CD30 Ligand, mFc Tag with the EC50 of 10.5ng/ml determined by ELISA.
HPLC of Human CD30 Ligand/TNFSF8 Protein
The purity of Human CD30 Ligand is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human CD30 Ligand/TNFSF8 Protein
Human CD30 Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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