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Human Betacellulin Protein 2502

$300.00$1,000.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Asp32-Gln118
SKU: 2502parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P35070

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Betacellulin (BTC) belongs to the epidermal growth factor (EGF) family of peptide ligands that are characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family.

molecular weight

The protein has a predicted MW of 36.52 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human Betacellulin Protein 2502

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Betacellulin (BTC) belongs to the epidermal growth factor (EGF) family of peptide ligands that are characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family.
Protein names
Probetacellulin [Cleaved into: Betacellulin (BTC)]
Gene names
BTC,BTC
Mass
9606Da
Function
Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Subellular location
[Betacellulin]: Secreted, extracellular space.; [Probetacellulin]: Cell membrane; Single-pass type I membrane protein.
Tissues
Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
Structure
Monomer. Interacts with EGFR and ERBB4.
Target Relevance information above includes information from UniProt accession: P35070
The UniProt Consortium

HPLC of Human Betacellulin~-Protein
The purity of Human Betacellulin is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human Betacellulin~-Protein
Human Betacellulin on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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