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Cynomolgus Siglec-15/CD33L3 Protein 4504

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Met60-Thr322
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

XP_005586866.2

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.

molecular weight

The protein has a predicted MW of 29.2 kDa. Due to glycosylation, the protein migratesto 33-43 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus Siglec-15/CD33L3 Protein 4504

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Data

ELISA with Cynomolgus Siglec-15/CD33L3 Protein
Immobilized Cynomolgus Siglec-15, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA.
HPLC of Cynomolgus Siglec-15/CD33L3 Protein
The purity of Cynomolgus Siglec-15 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus Siglec-15/CD33L3 Protein
Cynomolgus Siglec-15 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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