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Cynomolgus SG3/Secretogranin 3 Protein 2753

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Phe20-Leu468
SKU: 2753parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

I7G9U8

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs.

molecular weight

The protein has a predicted MW of 52.14 kDa. Due to glycosylation, the protein migrates to 58-70 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus SG3/Secretogranin 3 Protein 2753

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs.
Protein names
Secretogranin-3 (Secretogranin III)
Gene names
SCG3,SCG3
Mass
9541Da
Subellular location
Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein. Membrane ; Peripheral membrane protein. Secreted .
Target Relevance information above includes information from UniProt accession: I7G9U8
The UniProt Consortium

ELISA with Cynomolgus SG3/Secretogranin 3 Protein
Immobilized Cynomolgus SG3, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-SG3 Antibody, hFc Tag with the EC50 of 11.4ng/ml determined by ELISA.
HPLC of Cynomolgus SG3/Secretogranin 3 Protein
The purity of Cynomolgus SG3 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus SG3/Secretogranin 3 Protein
Cynomolgus SG3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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