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Cynomolgus/Rhesus macaque TNFSF15 Protein 2272

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Leu72-Leu251
SKU: 2272parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A2K5UA22

express system

HEK293

product tag

N-monomeric Fc

purity

> 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC

background

TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.

molecular weight

The protein has a predicted MW of 44.82 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus/Rhesus macaque TNFSF15 Protein 2272

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.
Protein names
Vascular endothelial cell growth inhibitor
Protein family
Tumor necrosis factor family
Mass
9541Da
Target Relevance information above includes information from UniProt accession: A0A2K5UA22
The UniProt Consortium

ELISA with Cynomolgus/Rhesus macaque TNFSF15 Protein
Immobilized Mouse DR3, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque TNFSF15, hFc Tag with the EC50 of 17.5ng/ml determined by ELISA (QC Test).
ELISA with Cynomolgus/Rhesus macaque TNFSF15 Protein
Immobilized Cynomolgus/Rhesus macaque TNFSF15, hFc Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 14.6ng/ml determined by ELISA.
HPLC of Cynomolgus/Rhesus macaque TNFSF15 Protein
The purity of Cynomolgus/Rhesus macaque TNFSF15 is greater than 90% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus/Rhesus macaque TNFSF15 Protein
Cynomolgus/Rhesus macaque TNFSF15 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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