ELISA with Cynomolgus PSMA/FOLH1 Protein 4262

Cynomolgus PSMA/FOLH1 Protein 4262

$345.00 – $1,150.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Lys44-Ala750

SKU: 4262parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5VNZ0
express system	HEK293
product tag	N-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells.
molecular weight	The protein has a predicted MW of 80.6 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus PSMA/FOLH1 Protein 4262

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells.
Protein names Folate hydrolase 1
Gene names FOLH1,FOLH1
Protein family Peptidase M28 family, M28B subfamily
Mass 9541Da
Subellular location Cell membrane ; Single-pass type II membrane protein. Membrane ; Single-pass type II membrane protein .
Target Relevance information above includes information from UniProt accession: A0A2K5VNZ0
The UniProt Consortium

Data

ELISA with Cynomolgus PSMA/FOLH1 Protein

Immobilized Cynomolgus PSMA, His Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Anti-PSMA Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).

The purity of Cynomolgus PSMA is greater than 95% as determined by SEC-HPLC

SDS-PAGE gel of Cynomolgus PSMA/FOLH1 Protein

Cynomolgus PSMA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.