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Cynomolgus MSLN/Mesothelin Protein 4878

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Asp296-Gly580
SKU: 4878parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A2K5TW94

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.

molecular weight

The protein has a predicted MW of 58.6 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus MSLN/Mesothelin Protein 4878

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Data

ELISA with Cynomolgus MSLN/Mesothelin Protein
Immobilized Cynomolgus MSLN, hFc Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Anti-MSLN Antibody, hFc Tag with the EC50 of 35.6ng/ml determined by ELISA (QC Test).
ELISA with Cynomolgus MSLN/Mesothelin Protein
Immobilized Human CA125, His Tag at 5ug/ml (100µl/Well). Dose response curve for Cynomolgus MSLN, hFc Tag with the EC50 of 4.8µg/ml determined by ELISA.
HPLC of Cynomolgus MSLN/Mesothelin Protein
The purity of Cynomolgus MSLN is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus MSLN/Mesothelin Protein
Cynomolgus MSLN on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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