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Cynomolgus MFAP4 Protein 2845

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Val60-Ala293
SKU: 2845parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A2K5TQS8

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Microfibril-associated glycoprotein 4 (MFAP4) is an extracellular matrix protein belonging to the fibrinogen-related protein superfamily. MFAP4 is produced by vascular smooth muscle cells and is highly enriched in the blood vessels of the heart and lung, where it is thought to contribute to the structure and function of elastic fibers. Genetic studies in humans have implicated MFAP4 in the pathogenesis of Smith-Magenis syndrome, in which patients present with multiple congenital abnormalities and mental retardation, as well as in the severe cardiac malformation left-sided congenital heart disease.

molecular weight

The protein has a predicted MW of 27.60 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus MFAP4 Protein 2845

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Microfibril-associated glycoprotein 4 (MFAP4) is an extracellular matrix protein belonging to the fibrinogen-related protein superfamily. MFAP4 is produced by vascular smooth muscle cells and is highly enriched in the blood vessels of the heart and lung, where it is thought to contribute to the structure and function of elastic fibers. Genetic studies in humans have implicated MFAP4 in the pathogenesis of Smith-Magenis syndrome, in which patients present with multiple congenital abnormalities and mental retardation, as well as in the severe cardiac malformation left-sided congenital heart disease.
Protein names
Microfibril associated protein 4
Gene names
MFAP4,MFAP4
Mass
9541Da
Target Relevance information above includes information from UniProt accession: A0A2K5TQS8
The UniProt Consortium

ELISA with Cynomolgus MFAP4 Protein
Immobilized Cynomolgus MFAP4, His Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Anti-MFAP4 Antibody, hFc Tag with the EC50 of 3.2ng/ml determined by ELISA.
HPLC of Cynomolgus MFAP4 Protein
The purity of Cynomolgus MFAP4 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus MFAP4 Protein
Cynomolgus MFAP4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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