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Cynomolgus IL-2 R gamma/CD132 Protein 4628

$225.00$750.00

Summary

  • Expression: HEK293
  • Pure: Yes (SDS-PAGE)
  • Amino Acid Range: Leu23-Asn254
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q38JL2

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE

background

The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.

molecular weight

The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus IL-2 R gamma/CD132 Protein 4628

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.
Protein names
Cytokine receptor common subunit gamma (Interleukin 2 receptor subunit gamma) (Membrane receptor Il2rg)
Gene names
IL2RG,IL2RG
Protein family
Type I cytokine receptor family, Type 5 subfamily
Mass
9544Da
Target Relevance information above includes information from UniProt accession : Q38JL2
The UniProt Consortium

Data

SDS-PAGE gel of Cynomolgus IL-2 R gamma/CD132 Protein
Cynomolgus IL-2 R gamma on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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