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Cynomolgus DLK1 Protein 2838

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Ala24-Cys306
SKU: 2838parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

XP_005562275

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.

molecular weight

The protein has a predicted MW of 31.26 kDa. Due to glycosylation, the protein migrates to 42-52 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus DLK1 Protein 2838

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.
Protein names
Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)]
Gene names
DLK1,DLK1 DLK
Mass
9606Da
Function
May have a role in neuroendocrine differentiation.
Subellular location
Membrane; Single-pass type I membrane protein. Cytoplasm .
Tissues
Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.
Structure
Monomer. Interacts with SH3RF2 (By similarity).
Post-translational modification
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
Target Relevance information above includes information from UniProt accession: P80370
The UniProt Consortium

HPLC of Cynomolgus DLK1 Protein
The purity of Cynomolgus DLK1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus DLK1 Protein
Cynomolgus DLK1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmidtitleauthorscitation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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