Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | XP_005562275 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. |
molecular weight | The protein has a predicted MW of 31.26 kDa. Due to glycosylation, the protein migrates to 42-52 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Cynomolgus DLK1 Protein 2838
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Ala24-Cys306
Cynomolgus DLK1 Protein 2838
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. |
Protein names Protein delta homolog 1 (DLK-1) (pG2) [Cleaved into: Fetal antigen 1 (FA1)] |
Gene names DLK1,DLK1 DLK |
Mass 9606Da |
Function May have a role in neuroendocrine differentiation. |
Subellular location Membrane; Single-pass type I membrane protein. Cytoplasm . |
Tissues Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue. |
Structure Monomer. Interacts with SH3RF2 (By similarity). |
Post-translational modification N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. |
Target Relevance information above includes information from UniProt accession: P80370 |
The UniProt Consortium |
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The purity of Cynomolgus DLK1 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus DLK1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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