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Cynomolgus CDCP1 Protein 2149

$345.00$1,150.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Phe30-Thr667
SKU: 2149parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

XP_005546930.2

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.

molecular weight

The protein has a predicted MW of 73.15 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus CDCP1 Protein 2149

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Protein names
CUB domain containing protein 1
Gene names
Cdcp1,Cdcp1
Mass
10116Da
Target Relevance information above includes information from UniProt accession: D3ZVA1
The UniProt Consortium

ELISA with Cynomolgus CDCP1 Protein
Immobilized Cynomolgus CDCP1, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 27.0ng/ml determined by ELISA.
HPLC of Cynomolgus CDCP1 Protein
The purity of Cynomolgus CDCP1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus CDCP1 Protein
Cynomolgus CDCP1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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