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Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein 2545

$300.00$1,000.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gln22-Asp117(CD3E) & Gln23-Thr113(CD3G)
SKU: 2545parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

Q95LI5.2(CD3E)&Q95LI7(CD3G)

express system

HEK293

product tag

C-His-Flag

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.

molecular weight

The protein has a predicted MW of 11.93 kDa (CD3E) and 11.52 kDa (CD3G). Due to glycosylation, the protein migrates to 13-23 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein 2545

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

ELISA with Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein
Immobilized Cynomolgus CD3E&CD3G, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-CD3 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA.
HPLC of Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein
The purity of Cynomolgus CD3E&CD3G is greater than 90% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein
Cynomolgus CD3E&CD3G on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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