Weight | 1 lbs |
---|---|
Dimensions | 9 × 5 × 2 in |
accession | XP_015300315.2 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Melanotransferrin is typically overexpressed in melanoma cells compared to other cell types – including cancer cells – and is efficiently sorted and secreted with nanovesicles, or so-called exosomes, due to its membrane-anchoring by a glycosylphosphatidylinositol. Melanotransferrin is exposed on the surface of exosomes and is accessible for antibody recognition. |
molecular weight | The protein has a predicted MW of 76.39 kDa. Due to glycosylation, the protein migrates to 77-90 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Cynomolgus CD228/MFI2 Protein 2195
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gly20-Cys709
Cynomolgus CD228/MFI2 Protein 2195
protein |
---|
Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
---|
Melanotransferrin is typically overexpressed in melanoma cells compared to other cell types - including cancer cells - and is efficiently sorted and secreted with nanovesicles, or so-called exosomes, due to its membrane-anchoring by a glycosylphosphatidylinositol. Melanotransferrin is exposed on the surface of exosomes and is accessible for antibody recognition. |
Protein names Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228) |
Protein family Transferrin family |
Mass 80215Da |
Function Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. {ECO:0000269|PubMed:7556058}. |
Subellular location [Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor. |
Tissues Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts. |
Target Relevance information above includes information from UniProt accession: P08582 |
The UniProt Consortium |
![]() |
The purity of Cynomolgus CD228 is greater than 95% as determined by SEC-HPLC. |
![]() |
Cynomolgus CD228 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
pmid | title | authors | citation |
---|---|---|---|
We haven't added any publications to our database yet. |
relevant to this product |
---|
# | ||
---|---|---|
Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. |
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.