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Cynomolgus BTLA Protein 2644

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Lys31-Pro152
SKU: 2644parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A2K5W7M7

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.

molecular weight

The protein has a predicted MW of 15.04 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Cynomolgus BTLA Protein 2644

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.
Protein names
B and T lymphocyte associated
Gene names
BTLA,BTLA
Mass
9541Da
Target Relevance information above includes information from UniProt accession: A0A2K5W7M7
The UniProt Consortium

ELISA with Cynomolgus BTLA Protein
Immobilized Cynomolgus BTLA, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-BTLA Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.
HPLC of Cynomolgus BTLA Protein
The purity of Cynomolgus BTLA is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Cynomolgus BTLA Protein
Cynomolgus BTLA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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