ELISA with Cynomolgus BAFFR/TNFRSF13C Protein 4400

Cynomolgus BAFFR/TNFRSF13C Protein 4400

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Ser7-Ala71

SKU: 4400parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	XP_001101623.2
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE
background	BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
molecular weight	The protein has a predicted MW of 7.7 kDa. Due to glycosylation, the protein migrates to 13-25 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus BAFFR/TNFRSF13C Protein 4400

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
Protein names BAFF receptor (BAFF-R) (Tumor necrosis factor receptor superfamily, member 13C)
Gene names TNFRSF13C,TNFRSF13C BAFF-R hCG_41562
Mass 18864Da
Target Relevance information above includes information from UniProt accession: Q5H8V1
The UniProt Consortium

Data

ELISA with Cynomolgus BAFFR/TNFRSF13C Protein

Immobilized Human BAFF (Trimer) , hFc Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Cynomolgus BAFFR, His Tag with the EC50 of 3.4ng/ml determined by ELISA (QC Test).

Immobilized Cynomolgus BAFFR, His Tag at 1µg/ml (100µl/Well) on plate.Dose response curve for Anti-BAFFR Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.

SDS-PAGE gel of Cynomolgus BAFFR/TNFRSF13C Protein

Cynomolgus BAFFR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.