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Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A1 (KVLEYVIKV) Monomer Protein 2058

$310.00$1,125.00

Summary

  • Expression: HEK293
  • Binding assay: Yes (SPR)
  • Amino Acid Range: Gly25-Thr206(Human HLA-A*02:01 α1&α2) & Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(mB2M) and KVLEYVIKV peptide
SKU: 2058parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A140T913(Human HLA-A*02:01 α1&α2)&P01897(Mouse HLd α3)&&P01887(Mouse B2M)&KVLEYVIKV

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE

background

MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.

molecular weight

The protein has a predicted MW of 48.00 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A1 (KVLEYVIKV) Monomer Protein 2058

protein
Size and concentration
100, 500µg and liquid
Form
Liquid
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped with dry ice.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
Protein names
Major histocompatibility complex, class I, A
Gene names
HLA-A,HLA-A
Protein family
MHC class I family
Mass
41449Da
Target Relevance information above includes information from UniProt accession: A0A140T913
The UniProt Consortium

SPR with Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A1 (KVLEYVIKV) Mon
Chimeric HLA-A*02:01(mα3)&mB2M&MAGE-A1 (KVLEYVIKV) Monomer, His Tag captured on CM5 Chip via Anti-His Antibody can bind HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) TCR with an affinity constant of 58.68 nM as determined in SPR assay (Biacore T200).
HPLC of Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A1 (KVLEYVIKV) Mono
The purity of Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A1 (KVLEYVIKV) Monomer is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A1 (KVLEYVI
Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A1 (KVLEYVIKV) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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