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Canine OSMR Protein 2501

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Glu28-Pro735
SKU: 2501parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A8I3MI11

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.

molecular weight

The protein has a predicted MW of 81.73 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Canine OSMR Protein 2501

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Protein names
Oncostatin M receptor
Gene names
OSMR,OSMR
Protein family
Type I cytokine receptor family, Type 2 subfamily
Mass
9615Da
Subellular location
Membrane ; Single-pass type I membrane protein .
Target Relevance information above includes information from UniProt accession: A0A8I3MI11
The UniProt Consortium

HPLC of Canine OSMR~-Protein
The purity of Canine OSMR is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Canine OSMR~-Protein
Canine OSMR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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