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Canine GDF15 Protein 5069

$450.00$1,500.00

Summary

  • Expression: E.coli
  • Functional: Yes (ELISA)
  • Amino Acid Range: Ala197-Val307
SKU: 5069parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A8C0TNP6

express system

E.coli

product tag

N-His

purity

> 95% as determined by Tris-Bis PAGE

background

Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.

molecular weight

The protein has a predicted MW of 13.12 kDa. The protein migrates to 15-20 kDa under reduced (R) condition and 23-26 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Canine GDF15 Protein 5069

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
Protein names
Growth differentiation factor 15
Gene names
GDF15,GDF15
Protein family
TGF-beta family
Mass
9615Da
Target Relevance information above includes information from UniProt accession: A0A8C0TNP6
The UniProt Consortium

ELISA with Canine GDF15 Protein
Immobilized Canine GDF15, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-GDF15 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA (QC Test).
ELISA with Canine GDF15 Protein
Immobilized Canine GDF15, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 48.3ng/ml determined by ELISA.
SDS-PAGE gel of Canine GDF15 Protein
Canine GDF15 on Tris-Bis PAGE under reduced (R) condition and Non reducing (N) condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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